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. 2021 Sep 9;11:18017. doi: 10.1038/s41598-021-97520-z

Table 6.

Dosimetric evaluation of the targets for the SEB-HFWBI or SIB-HFWBI treatment plan in the supine and prone positions (median).

Parameters Supine Prone Z-value P-value
SEB-HFWBI
PTVTB
Dmean (Gy) 53.11 (51.78–54.79) 53.57 (51.42–54.24)  − 2.478 0.013
V100% 99.35 (95.80–99.97) 99.30 (92.00–99.90)  − 0.577 0.564
PTVWB
V100% 98.10 (96.40–99.60) 98.30 (86.50–100.00)  − 0.748 0.455
CI 0.63 (0.47–0.75) 0.69 (0.50–0.82)  − 3.340 0.001
PTVWB-PTVTB
V100% 12.65 (4.00–25.70) 20.4 (5.20–32.40)  − 3.908 0.000
SIB-HFWBI
PTVTB
Dmean (Gy) 51.04(49.77–52.66) 51.95 (50.13–57.98)  − 2.036 0.021
V100% 98.55 (95.50–99.80) 98.40 (93.70–99.90)  − 0.068 0.946
PTVWB
V100% 96.55 (86.30–98.50) 96.55 (95.10–98.40)  − 0.216 0.829
CI 0.66 (0.50–0.77) 0.72 (0.52–0.83)  − 3.501 0.000
PTVWB-PTVTB
V100% 8.60 (2.60–14.70) 13.55 (3.80–36.20)  − 4.165 0.000

TB tumor bed, PTVTB planning target volume for TB, WB whole breast, PTVWB planning target volume for WB, PTVWB-PTVTB the target volume obtained by subtracting the PTVTB from the PTVWB, SIB simultaneous integrated boost, SEB sequential integrated boost, HFWBI hypofractionated whole-breast irradiation, CI conformal index, Dmean mean dose, V100% the PTV coverage percent of the 100% prescribed dose line including PTVTB, PTVWB, PTVWB-PTVTB in the treatment plan under supine and prone positions.