. 2021 Sep 9;11:17928. doi: 10.1038/s41598-021-96986-1

Table 2.

Prepatent (T1%) periods and statistical significance of protective efficacy.

Challenge	Comparison	Poly (I:C)			Montanide ISA720
Challenge	Comparison	NLP-CSP_CT vs. Adj	NLP-CSP_R vs. Adj	NLP-CSP_CT vs. NLP-CSP_R	NLP-CSP_CT vs. Adj	NLP-CSP_R vs. Adj	NLP-CSP_CT vs. NLP-CSP_R
Pb-PvCSP210	Median T1%	5.15 vs. 4.6	4.85 vs. 4.6	5.15 vs. 4.85	5.6 vs. 4.8	5.3 vs. 4.8	5.6 vs. 5.3
Pb-PvCSP210	p values	p = 0.0008	p = 0.0136	n.s. p = 0.1026	p = 0.0005	p = 0.0068	p = 0.0192
Pb-PvCSP247	Median T1%	4.7 vs. 4.4	4.5 vs. 4.4	4.7 vs. 4.5	5.5 vs. 4.5	5.35 vs. 4.5	5.5 vs. 5.35
Pb-PvCSP247	p values	p = 0.0049	n.s. p = 3797	p = 0.0136	p = 0.0005	p = 0.0005	n.s. p = 0.2798
Pb-PvCSP-like G10	Median T1%	5.6 vs. 5.05	5.7 vs. 5.05	5.6 vs. 5.7	5.75 vs. 5	5.85 vs. 5	5.75 vs. 5.85
Pb-PvCSP-like G10	p values	p = 0.0005	p = 0.0012	n.s. p = 0.9949	p = 0.0007	p = 0.0007	n.s. p = 0.9910

Significant differences (p < 0.05) were analyzed by applying the log-rank (Mantel-Cox) test. n = 6 mice/group. n.s.: not significant differences.