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. 2021 Sep 9;5:25. doi: 10.1038/s41538-021-00108-0

Fig. 2. Effects of Gly-Sar and cytochalasin D on transport of Cblin pentapeptides in Caco-2 cells.

Fig. 2

Effects of 10 mM Gly-Sar on transport of 1 mM Asp-Gly-pTyr-Met-Pro (a) and Asp-Gly-Tyr-Met-Pro (b) across Caco-2 cell monolayers for 60 min. Basolateral peptide concentrations were determined after 60 min by LC–TOF/MS. Effects of cytochalasin D on transport of 1 mM Asp-Gly-pTyr-Met-Pro (c) and Asp-Gly-Tyr-Met-Pro (d) across Caco-2 cell monolayers for 60 min. Caco-2 cell monolayers were incubated with or without cytochalasin D (0.5 μg/mL) for 30 min. Basolateral peptide concentrations were determined by LC–TOF/MS. Values are expressed as means ± SEM, n = 4–6. *P < 0.05, **P < 0.01. NS, not significant.