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Pharmacokinetics after oral administration of Asp-Gly-Tyr-Met-Pro to 8-week-old Sprague-Dawley rats.
| Measured parameters | Oral dose (100 mg/kg BW) |
|---|---|
| Cmax (pmol/mL plasma) | 2.78 ± 0.17 |
| tmax (min) | 15 |
| AUC0–60 min (pmol/min/mL plasma) | 100.35 ± 23.40 |
| t1/2 (min) | 28 |
Data are expressed as means ± SEM (n = 5).
AUC0–60 min, area under plasma concentration vs. time curve; BW, body weight; Cmax, maximum plasma concentration; t1/2, elimination half-life; tmax, time to reach peak plasma concentration.
