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. 2021 Sep 10;48(1):1–15. doi: 10.1007/s00134-021-06514-y

Table 2.

Factors associated with outcomes after ECPR

Risk factors Effect on survival with functional recovery OR for survival RR or HR for mortality Modifiable?
Pre-arrest
 Older age Unfavorable Age > 60, OR 0.54 [13] Age ≤ 65, HR 0.46 [15] No
 Shockable rhythm Favorable OR 1.39–3.93 [13, 23, 41, 51, 53, 55]

HR 0.58 [14]

Asystole, RR 1.36 [56]

PEA, RR 1.2 [56]

No
Intra-arrest
 Shorter no-flow or low-flow time Favorable

CPR < 30 min (vs > 30 min), OR 4.13 [13]

CPR < 45 min (vs > 45 min), OR 3.53 [13]

CPR < 60 min (vs > 60 min), OR 9.82 [13]

For every 10 min shorter CPR, OR 1.95 [51]

CPR duration per min increase, OR 0.97 [41]

CPR < 45 min vs CPR > 58 min, OR 3.66 [52]

CPR per min increase, HR 1.007 [14]

CPR duration ≤ 35 min, HR 0.37 [15]

Yes
 High-quality CPR Favorable N/A N/A Yes
Post-arrest
 Targeted temperature management Favorable N/A N/A Yes
 Percutaneous coronary intervention Favorable OR 1.52 [13] HR 0.36 [15] Yes

CPR cardiopulmonary resuscitation, N/A not available, PEA pulseless electrical activity