Figure 2.
Immunohistochemical and molecular findings of GNET. The neoplastic cells expressed S-100 [(A), X200] and intact SMARCA4(BRG1) [(B), X100]. Syn [(C), X200] was focally positive. The Ki67 [(D), X200] proliferative index was low. Staining for pancytokeratin [(E), X200] was negative. FISH using EWSR1 break apart probe showed red and green split apart signals, suggesting EWSR1 gene rearrangement [(F), X1000].