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. 2021 Aug 27;12:711433. doi: 10.3389/fimmu.2021.711433

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Copyright © 2021 Xu, Chen, Hu and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The Landscape of Immune Cell Infiltration in the TIME context. (A) Unsupervised clustering of tumor-infiltrating immune cells in BRCA patients. Rows represent tumor-infiltrating immune cells, and columns represent samples. (B) Kaplan-Meier curves for the overall survival (OS) of all BRCA patients in discrete ICI clusters. (C) The subpopulation of infiltrating immune cells, immune score, and stromal score in three ICI clusters. (D) Intrinsic connection of the infiltrating immune cells and immune scores. The asterisks represented the statistical p value (*P < 0.05; **P < 0.01; ***P < 0.001), ns, No Significance.