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. 2021 Aug 27;12:676813. doi: 10.3389/fphar.2021.676813

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Copyright © 2021 Huang, Yuan, Liu, Liu, Wung and Chuang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of capsaicin on oral cancer cell growth and apoptosis. (A) The cell proliferation of HSC-3 and SAS cells treated with different concentrations of capsaicin, as measured by RTCA. (B) Cell viability after capsaicin treatment for 48 h was assayed by Cell Counting Kit-8 (CCK-8). (C,D) The levels of apoptosis after capsaicin treatment for 48 h were analyzed by flow cytometry, and apoptosis-related proteins were detected by Western blot analysis (E). Data are representative of three to six independent experiments.