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Epithelial cell proliferation in the distal colon of Apc+/+-FCCC wild type mice (‘WT’; n=4), tumor-free Apc+/Min-FCCC mice (‘TF Min’; n=6) and tumor-bearing Apc+/Min-FCCC mice (‘TB Min’; n=6). Bars represent mean ± S.E.M. (A) Fold change in proliferative index in tumor-bearing vs tumor-free mice = 0.9; Welch’s t-test p = 0.65. (B) Fold change in size of the proliferative zone in tumor-bearing vs tumor-free mice = 0.8; Welch’s t-test p = 0.15.
