Fig. 5.

Variation of correlation of small-scale features extracted from individual versus atlas-based tractography with lesion load for the diffusion dataset. Each point is a patient. Spearman correlation and ICC(3,1) agreement between the two methods are computed across nodes for all patients and are shown on the y-axis. The total lesion volume (TLV) estimated from either manual (in yellow) or LeMan-PV lesion segmentations (in blue) on the x-axis. Labels in the graph indicate patient with generally high or low agreement, for which details are provided in Supplementary Fig. 3.