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. 2021 Aug 27;12:735700. doi: 10.3389/fphar.2021.735700

TABLE 2.

Summary of adverse events.

Elderly 0.2 mg/kg (N = 8) Elderly 0.3 mg/kg (N = 8) Elderly 0.4 mg/kg (N = 8) Non-elderly 0.4 mg/kg (N = 8) Total (N = 32)
n (%) n (%) n (%) n (%) n (%)
Total 3 (37.5) 2 (25.0) 4 (50.0) 1 (12.5) 10 (31.3)
Hyperglycemia 2 (25.0) 0 (0) 1 (12.5) 0 (0) 3 (9.4)
Hypoalbuminemia 0 (0) 0 (0) 2 (25.0) 0 (0) 2 (6.3)
Respiratory depression 0 (0) 1 (12.5) 1 (12.5) 0 (0) 2 (6.3)
Supraventricular arrhythmia 0 (0) 0 (0) 1 (12.5) 0 (0) 1 (3.1)
First degree atrioventricular block 0 (0) 0 (0) 1 (12.5) 0 (0) 1 (3.1)
Blood pressure decreased 0 (0) 1 (12.5) 1 (12.5) 0 (0) 2 (6.3)
Hematuria 1 (12.5) 0 (0) 0 (0) 0 (0) 1 (3.1)
Anemia 0 (0) 0 (0) 0 (0) 1 (12.5) 1 (3.1)

n: the subject number; %: the percentage of the AE.