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. 2021 Aug 15;13(8):8728–8741.

Figure 4.

Figure 4

miR590-5p inhibition promoted the cell viability and inhibited apoptosis of IL-1β-induced chondrocytes. Human chondrocytes were treated with 10 ng/mL IL-1β, and then transfected with NC or miR590-5p inhibitors (100 nM) for 24 h. A: The expression of miRNA-590-5p was detected by qPCR assay. B: CCK-8 assay was performed to evaluate the viability of chondrocytes cells. C: The mRNA levels of Bcl-2, Bax and Caspase-3 were detected by RT-PCR assay. D: Western blot analysis was carried out to detect Bcl-2, Bax and Caspase-3. E: Bar graph shows quantification results for Bcl-2, Bax and Caspase-3. *P < 0.05, **P < 0.01 and ***P < 0.001; #P < 0.05, ##P < 0.01, ##P < 0.01, IL-1β+ inhibitors versus IL-1β+ inhibitors NC.