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. 2021 Aug 15;13(8):8728–8741.

Figure 5.

Figure 5

Human chondrocytes were treated with 10 ng/mL IL-1β, and then transfected with miR590-5p mimics or inhibitors (100 nM) for 48 h. miR590-5p promoted the IL-1β-induced inflammatory response in chondrocytes. A: The level of IL-6 in chondrocytes treated by miR590-5p mimics; B: The level of IL-8 in chondrocytes treated by miR590-5p mimics; C: The level of TNF-α in chondrocytes treated by miR590-5p mimics; D: The level of IL-6 in chondrocytes treated by miR590-5p inhibitor; E: The level of IL-8 in chondrocytes treated by miR590-5p inhibitor; F: The level of TNF-α in chondrocytes treated by miR590-5p inhibitor; *P < 0.05, **P < 0.01 and ***P < 0.001; #P < 0.05, ##P < 0.01 and ###P < 0.001, IL-1β+ mimics or inhibitors versus IL-1β+ NC.