Figure 2.

Galangin suppressed IL-1β-induced inflammation. A, B. Chondrocytes were incubated with or without IL-1β (10 ng/mL) and with indicated concentrations of galangin (0, 4, 8, 16 μM) for 24 h. The expressions of TNF-α, INOS, IL-6, MMP3, MMP9, and MMP13 were detected via qPCR. C, D. The expression of iNOS and COX-2 was measured via western blot analysis. All data are presented as mean ± SD. Significant differences among groups are indicated as ##P < 0.001 vs. control group; *P < 0.05, **P < 0.01, and ***P < 0.001 vs. IL-1β alone treatment group, n = 3.