Galangin inhibited IL-1β-stimulated activation of the NF-κB pathway and the JNK and ERK pathways. A, B. The expression of p-p65, p65, IκBα, and β-actin was detected via western blotting and quantified by image J. C, D. The expression of p-ERK, ERK, p-JNK, JNK, p-p38, and p38 was detected by western blotting and quantified by Image J. E, F. The expression of PI3K, p-AKT, and AKT was detected via western blotting and quantified by Image J. All data are presented as mean ± SD. Significant differences among groups are indicated as *P < 0.05, **P < 0.01, and ***P < 0.001 vs. IL-1β treatment group, n = 3.