Table 2.
Cord blood analytes in preterm infants and term-born controls.
| Analyte (pg/ml) | Preterm n = 55 | Term n = 59 | p-value* | ||
|---|---|---|---|---|---|
| Median | Q1, Q3 | Median | Q1, Q3 | ||
| BDNF | 22.27 | 6.04, 36.90 | 62.33 | 43.18, 113.68 | <0.001 |
| C3 | 3081995.73 | 1858060.85, 4569905.86 | 4447458.83 | 3520957.75, 5613382.51 | <0.001 |
| C5a | 3694.52 | 2420.56, 11470.85 | 7136.48 | 4059.83, 9443.64 | 0.004 |
| C9 | 1236.73 | 215.00, 6901.99 | 12628.69 | 3608.60, 43156.07 | <0.001 |
| CRP | 100.88 | 89.00, 12054.79 | 89.00 | 89.00, 89.00 | <0.001 |
| IL-1β | 0.26 | 0.26, 0.49 | 0.11 | 0.02, 0.34 | 0.016 |
| IL-6** | 0.45 | 0.45, 6.00 | 0.45 | 0.45, 0.45 | <0.001 |
| IL-8 | 12.05 | 5.75, 81.08 | 8.29 | 4.89, 14.71 | 0.134 |
| IL-18 | 25.62 | 10.35, 38.34 | 41.27 | 27.50, 54.78 | 0.003 |
| MCP-1 | 109.09 | 68.69, 210.75 | 48.12 | 38.54, 66.63 | <0.001 |
| MIP-1β | 12.01 | 7.47, 18.82 | 9.72 | 6.88, 18.24 | 0.331 |
| MMP-9 | 14000.68 | 4485.50, 40077.02 | 155885.89 | 87194.67, 358084.73 | <0.001 |
| RANTES | 1460.12 | 702.74, 2754.37 | 3127.55 | 1817.10, 5295.39 | <0.001 |
| TNF-α | 0.27 | 0.27, 0.37 | 0.27 | 0.27, 0.27 | 0.304 |
*Mann Whitney U test to compare ranks (Bonferroni corrected threshold p < 0.004). **IL-6: For preterm infants: 27 were below the lower limit of detection (0.45pg/ml), and the range for the remaining 28 was 0.46-249.56pg/ml. For term infants: 50 were below the lower limit of detection and the range for the remaining 9 was 0.66-11.46pg/ml.