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. 2021 Aug 27;11:720400. doi: 10.3389/fonc.2021.720400

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Copyright © 2021 Zhou, Bai, Long, Hu and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of lncRNA-TF positive feedback loops. (A, B) Motif scanning results of lncRNA promoter and enhancer regions. Heatmap represents the Pearson correlation coefficients between lncRNAs and TFs. Size represents the number of motifs in DNA regions. (C) Cytoscape visualization of lncRNA-TF positive feedback loops. (D, E) The prognostic effects of ELK4-lncRNA feedback pairs and BDP1-lncRNA feedback pairs in LUAD.