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. 2021 Aug 27;12:693701. doi: 10.3389/fphar.2021.693701

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Copyright © 2021 Wei, Hou, Liang, Fang, Dou, Wang, Sai, Xu, Ma, Zhang, Cheng, Wang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SNS inhibited JAK2/STAT3 signal against NAFLD. (A) Expressions of signal transducer and activator of transcription (STAT3) and phosphorylated STAT3 (p-STAT3) were determined by Western blotting. (B) Quantitative analysis of p-STAT3:STAT3 expression ratio. (C) Expressions of Janus Kinase 2 (JAK2) and phosphorylated JAK2 (p-JAK2) were determined by Western blotting. (D) Quantitative analysis of p-JAK2:JAK2 expression ratio. Data are shown as mean ± SD (n = 3). ^# p < 0.05, ^## p < 0.01, ^### p < 0.001 when compared with the Chow group, *p < 0.05, **p < 0.01, ***p < 0.001 when compared with HFD group.