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. 2021 Aug 27;12:666447. doi: 10.3389/fimmu.2021.666447

Table 2.

Bacterial and viral causes of fever in infants <90 days of age.

Invasive bacterial infection (IBI) Viral infection
n = 25 (49.0%) n = 14 (27.5%)
Focus Urosepsis n = 18 URT infection n = 6
BC-positive n = 9 Meningitis n = 4
Meningitis n = 1 Pneumonia n = 3
Endocarditis n = 1 Gastroenteritis n = 1
Pneumonia n = 2
Pathogen E. coli n = 15 Enterovirus n = 7
GBS n = 5 Rhinovirus n = 3
Kl. oxytoca n = 1 Rotavirus n = 1
E. faecalis n = 2 RSV n = 1
Kl. pneumoniae n = 2 Corona NB n = 1
Corona NL 63 n = 1

URT, Upper respiratory tract; BC, blood culture; GBS, group B streptococcus (streptococcus agalactiae); RSV, respiratory syncytial virus; URT infection: virus detected by multiplex PCR from nasopharyngeal aspirate; for n = 12 cases (23.5%) of suspected LOS no microbial pathogen was detected (unknown cause of fever).