Table 1.

Effect of different inflammatory stimuli on pituitary GH secretion. Upward arrows indicate increased and downward arrows decreased pituitary GH secretion in response to the inflammatory stimuli.

Reference	Inflammatory Stimuli	Specie/Cell Culture	Pituitary GH Secretion (↑/↓)
[3]	Low LPS doses (5, 10, 50 and 100 µg/kg, i.p.)	Rodents	↑
[2,3,12,13]	High LPS doses (100, 250, 500 and 1000 microg/kg, i.p.)	Rodents	↓
[6]	LPS (4 ng/kg, i.v.)	Humans	↑
[3]	LPS (0.1 and 10 ng/mL)	Pituitary cell culture (rodents)	↑
[2,7,8]	Experimental arthritis	Rodents	↓
[9,10]	Cystic fibrosis, inflammatory bowel disease	Humans	↓
[11]	Critical ill patients:	Humans
	acute phase		↑
	chronic phase		↓