Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of Parkinson’s gene therapy strategies and targets. The first approach (AP1) focuses on stimulating dopamine synthesis by targeting AADC and TH in dopaminergic neurons of the Substantia nigra. The second approach (AP2) focuses on GLF ligands. A third approach (AP3) focuses on the stimulation of mitophagy. Finally, the fourth approach (AP4) aims to reduce the presence of α-synuclein that ultimately generates Lewy bodies. Designed with biorender.com.
