Table 4.

LncRNAs involved in pathogenesis of hypertrophic cardiomyopathy.

lncRNA	Mechanism of Action
Mhrt	Protect against pathological hypertrophic cardiomyopathy by inhibiting the Brg1-Hdac-Parp chromatin repressor complex to prohibit initiation of Myh6-to-Myh7 switch 2. Reduce myocardin acetylation/expression via HDAC5
MIAT	Contributing factor to the pathogenesis of hypertrophic cardiomyopathy and act by mediating the expression of miR-29a-3p
H19	Targets CaMKIIδ through miR-675 and functions as a negative regulator of hypertrophic cardiomyopathy
CAIF	Downregulated in end-stage cardiomyopathy
uc004cov.4	Upregulation leads to Hypertrophic obstructive cardiomyopathy-unknown mechanism
uc022bqu.1	Upregulation leads to Hypertrophic obstructive cardiomyopathy- unknown mechanism