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. 2021 Aug 26;22(17):9219. doi: 10.3390/ijms22179219

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structure of the PFNA operon across different members of the genus Bifidobacterium. Group 1—the cluster consists of five genes: B. actinocoloniiforme, B. angulatum, B. asteroides, B. biavatii, B. coryneforme, B. indicum, B. lemurum, B. merycicum, B. scardovii, B. thermacidophilum (group 1) and B. breve (there is fusion of genes encoding the fibronectin type III domain-containing protein and AAA-ATPase). Group 2—the cluster contains between six and seven genes: B. adolescentis, B. animalis, B. bohemicum, B. bombi, B. boum, B. catenulatum, B. choerinum, B. commune, B. cuniculi, B. dentium, B. gallicum, B. moukalabense, B. pseudocatenulatum, B. pseudolongum, B. reuteri, B. ruminantium, B. thermophilum and B. kashiwanohense (the gene prpC is absent), B. stellenboschense (the gene BLGT_RS02790 is absent). Group 3—the cluster contains eight genes: B. aesculapii, B. bifidum, B. longum, B. saguini. The arrows indicate the direction of transcription of the genes [54]. Adapted from [60].