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. 2021 Sep 2;22(17):9552. doi: 10.3390/ijms22179552

Figure 6.

Figure 6

Graphical representations and CD spectra of the preferential structure of modified DNA. (a) DNA structure including purines modified with methylation (left), bromination (middle), and arylation (right); (b) CD spectra of 8-methyl ribo-guanosine incorporating oligomer stabilized the Z-DNA at low salt concentrations; (c) B-Z transition monitored by CD spectra. 8-Bromo-2′-deoxyguanosine containing an octamer sequence (d(CGTBrGCACG)2) dramatically stabilized the Z-form in low-salt physiological conditions; (d) CD spectra of the natural sequence and modified hairpin sequence in salt physiological condition from Ref. [89]. Arrows indicate the signature band of Z-DNA. Copyright (2003), (2004), and (2014), American Chemical Society.