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. 2021 Aug 31;22(17):9485. doi: 10.3390/ijms22179485

Figure 7.

Figure 7

Blockade of the DA D1 receptor partially attenuated acute β-PEA-induced circling behaviors in mice. (A) Experimental timeline for the open-field test. (B–G) Effect of SCH23390 (0.02 mg/kg) on circling (B), head-twitching response (D), and locomotor activity (F) for 30 min and temporal changes in circling (C), head-twitching response (E) behaviors and locomotor activity (G) in a 5-min time interval after β-PEA administration. * p < 0.05, *** p < 0.001 vs. saline control group. VEH, vehicle; β-PEA, β-phenylethylamine. n = 6 per group.