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Metformin treatment downregulates profibrotic genes in postinfarcted myocardium. (A) qRT-PCR quantification of the expression level of the myofibroblast marker αSMA. (B) qRT-PCR quantification of the expression level of the collagen type III. Data are presented as mean ± SEM. One-way ANOVA followed by Bonferroni’s post hoc test: * p < 0.05 vs. control (C), ** p < 0.01 vs. control (C), § p < 0.05 vs. I/R.
