Table 6.
Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of compound 18.
| Compound | Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) in µg/mL | |||||
|---|---|---|---|---|---|---|
| Gram-Positive Bacteria | Gram-Negative Bacteria | |||||
| S. aureus | S. epidermidis | B. subtilis | P. aeruginosa | E. coli | P. vulgaris | |
| MIC MBC |
MIC MBC |
MIC MBC |
MIC MBC |
MIC MBC |
MIC MBC |
|
| 18 | 50 50 |
50 100 |
25 50 |
25 50 |
50 50 |
100 100 |
| Ampicillin | 6.25 | 12.5 | 12.5 | - | - | - |
| Levofloxacin | - | - | - | 12.5 | 6.25 | 12.5 |