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. 2021 Aug 28;13(17):4353. doi: 10.3390/cancers13174353

Figure 1.

Figure 1

The protective effect of endocannabinoid system in intestinal inflammation. See text for discussion. Created with BioRender.com (accessed on 10 August 2021). Abbreviations: 2-AG—2-arachidonoyl glycerol; AEA—anandamide; CB1—cannabinoid receptor 1; CB2—cannabinoid receptor 2; COX2—cyclooxygenase 2; IFN-γ—interferon γ; ERK—extracellular regulated kinase; FAK—focal adhesion kinase; IL-1β—interleukin 1β; IL-6—interleukin 6; IL-10—interleukin 10; IL-12—interleukin 12; IL-23—interleukin 23; NFκB—nuclear factor κB; STAT3—signal transducer and activator of transcription 3; PGE2—prostaglandin E2; PLC—phospholipase C; TH1—T-helper 1; TH2—T-helper 2; TH17—T-helper 17; TLR 4—Toll-like receptor 4; TNF-α—tumor necrosis factor α.