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. 2021 Aug 24;22(17):9116. doi: 10.3390/ijms22179116

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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HBV status and the incidence of hepatitis related to HBV reactivation in SLE patients. SLE patients were categorized according to hepatitis B surface antigen (HBsAg), antibody to hepatitis B core antigen (anti-HBc), and antibody to hepatitis B surface antigen (anti-HBs) status. HBV reactivation in HBsAg-positive patients was defined as either an increase in HBV DNA > 1 Log10 IU/mL compared with baseline or HBV DNA > 20,000 IU/mL in cases without baseline HBV viral load after diagnosis or the use of immunosuppressive agents. HBsAg reverse seroconversion (RS) in HBsAg-negative/antibody to hepatitis B core antigen-positive patients was defined as reappearance of HBsAg in the serum.