Table 3.
Correlations between the improvements in various outcomes.
| NRS1 | NRS2 | mMRC | 6MWD | VC | TLC | FEV1 | PaO2 | TLCO | PImax | D-dimers | CRP | EQ-5D-5L | VAS | BFI | PHQ-9 | GAD-7 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NRS1 | 1 | 0.341 ** | 0.159 | −0.223 * | 0.010 | 0.058 | 0.143 | −0.004 | 0.141 | 0.153 | -0.014 | −0.058 | 0.134 | 0.077 | 0.193 | 0.196 | 0.261 * |
| NRS2 | 1 | 0.220 | 0.187 | 0.159 | 0.187 | 0.192 | −0.120 | 0.075 | 0.073 | -0.077 | −0.164 | 0.363 ** | 0.273 * | 0.242 * | 0.204 | 0.348 ** | |
| mMRC | 1 | 0.074 | 0.099 | −0.127 | 0.092 | −0.038 | −0.012 | 0.030 | -0.058 | −0.050 | 0.164 | 0.405 ** | 0.313 ** | 0.158 | 0.265 * | ||
| 6MWD | 1 | 0.065 | 0.058 | 0.027 | 0.281 ** | 0.191 | −0.280 ** | 0.195 | 0.273 * | 0.279 * | 0.244 * | 0.203 | 0.124 | 0.045 | |||
| VC | 1 | 0.480 ** | 0.842 ** | 0.249 * | 0.126 | 0.338 ** | 0.295 * | 0.146 | 0.127 | 0.118 | 0.179 | 0.233* | −0.076 | ||||
| TLC | 1 | 0.305 ** | 0.205 * | 0.227 * | 0.222 * | 0.305 * | 0.108 | 0.199 | −0.020 | 0.090 | 0.061 | 0.014 | |||||
| FEV1 | 1 | 0.286 ** | 0.222 * | 0.248 * | 0.229 | 0.197 | 0.124 | 0.145 | 0.145 | 0.290 * | 0.077 | ||||||
| PaO2 | 1 | 0.316 ** | −0.068 | 0.165 | 0.281 | 0.006 | −0.128 | −0.061 | 0.055 | 0.017 | |||||||
| TLCO | 1 | −0.003 | 0.306 * | 0.200 | 0.047 | 0.010 | 0.068 | 0.054 | 0.066 | ||||||||
| PImax | 1 | 0.173 | 0.097 | −0.021 | 0.157 | −0.064 | −0.197 | −0.106 | |||||||||
| D-dimers | 1 | 0.600 ** | 0.162 | 0.155 | 0.062 | −0.041 | −0.171 | ||||||||||
| CRP | 1 | −0.092 | 0.102 | −0.129 | −0.158 | −0.118 | |||||||||||
| EQ-5D-5L | 1 | 0.296 ** | 0.419 ** | 0.059 | 0.106 | ||||||||||||
| VAS | 1 | 0.279 * | 0.077 | 0.318 ** | |||||||||||||
| BFI | 1 | 0.0555 ** | 0.498 ** | ||||||||||||||
| PHQ-9 | 1 | 0.473 ** | |||||||||||||||
| GAD-7 | 1 |
Notes: Values in gray indicate nonsignificant results; values in bold indicate correlation coefficients of ≥0.3; *: p < 0.05; **: p < 0.01; 6MWD: 6-min walking distance; BFI: Brief Fatigue Inventory; CRP: C-reactive protein; EQ-5D: 5-level EQ-5D questionnaire; FEV1: Forced expiratory volume in one second: GAD-7: Generalized Anxiety Disorder-7; mMRC: modified Medical Research Council; NRS1: Numeric Rating Scale for intensity of resting dyspnea; NRS2: Numeric Rating Scale for intensity of exertional dyspnea; PaO2: partial pressure of O2; PHQ-9: Patient Health Questionnaire 9; PImax: maximal inspiratory pressure; TLC: total lung capacity; TLCO: diffusion capacity of the lungs for carbon monoxide; VAS: visual analogue scale; VC: vital capacity.