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. 2021 Aug 24;22(17):9135. doi: 10.3390/ijms22179135

Figure 6.

Figure 6

Analysis of peroxisome biogenesis in miR-29a mimic or antisense oligonucleotide-treated bone marrow mesenchymal stem cells during adipogenic differentiation. Images of Pmp70 immunofluorescence-labeled peroxisomes (a); scale bar, 25 µm (upper panel); 10 µm (lower panel). Forced miR-29a expression reduced peroxisomal granule formation (b), Pex14 (c), and Pmp70 (d) expression, whereas miR-29a knockdown promoted peroxisome formation. Mean ± S.E. is calculated from 3 experiments. * p < 0.05 upon ANOVA test and Bonferroni post hoc test. Scramble, scrambled control; miR-29a, miR-29a mimic; miR-29a-AS, miR-29a antisense oligonucleotide.