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Synthetic cannabinoids and their therapeutic window for pain.
| Synthetic Cannabinoids | Therapeutic Window | References | |
|---|---|---|---|
| 1. | HU-308 and AM-124 (CB2R agonists) | Pain and inflammation | [6] |
| 2. | Pyrimidinecarboxamide (and its derivatives) (CB2R modulators) | Acute, chronic, and inflammatory pain | [6] |
| 3. | JWH-133 (intrathecal administration) | Reduction in post-operative hypersensitivity | [57] |
| 4. | Peripherally restricted CB1R agonists | Chronic pain | [58] |
