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. 2021 Aug 31;22(17):9472. doi: 10.3390/ijms22179472

Table 13.

Drugs that inhibit endocannabinoid metabolism and the deactivation of the ECS.

Drugs That Inhibit the Deactivation Biological Effect(s) and/or Mechanism of Action Reference
i. AM404 Blocks endocannabinoid transport [136]
ii. OMDM-8 Blocks endocannabinoid transport [136]
iii. AM1172 (University of Connecticut/University of California) Blocks endocannabinoid transport [136]
iv. FAAH (fatty acid amide hydrolase) Deactivates/degrades AEA [136]
v. MAGL (monoacylglycerol) Deactivates/degrades 2-AG [136]