Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 31;13(17):4405. doi: 10.3390/cancers13174405

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of niraparib treatment on tumor cell survival and proliferation: (A) Cell viability analysis of established CCA cell lines (KMCH-1, HuCCT1) after niraparib treatment for 72 h. (B) Cell viability of patient derived xenograft lines (CHNG6, CHNG31) after niraparib treatment for 72 h. (C) Colony formation ability of KMCH-1 cells after niraparib treatment. Bar graph showing average colony number after different treatments. (D) Spheroid formation of CHNG31 after treatment with various concentrations of niraparib. Cell cycle analysis of (E) KMCH-1 or (F) CHNG31 after niraparib treatment for 72 h. Bar graphs showing analysis of different cell cycle phases after vehicle or niraparib treatment. * p < 0.05. p values were calculated using the two-sided Student’s t test and data presented as mean + stdev.