TABLE 1.
Sensitivity and specificity of tests for detection of antibodies to HIV-1 and HIV-2 with samples positive and negative for HIV-1 by EIAa
Test | Serum
|
Plasma
|
Whole blood
|
Serum
|
Plasma
|
Whole blood
|
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of HIV-1-posi-tive serum samples positive by EIA
|
Sensi-tivity (%) | No. of HIV-1-posi-tive plasma samples positive by EIA
|
Sensi-tivity (%) | No. of HIV-1-positive whole-blood samples positive by EIA
|
Sensi-tivity (%) | No. of HIV-1-nega-tive serum samples negative by EIAa
|
Specifi-city (%) | No. of HIV-1-nega-tive plasma samples negative by EIA
|
Specifi-city (%) | No. of HIV-1 negative whole-blood samples negative by EIA
|
Specifi-city (%) | |||||||
Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | |||||||
Determine HIV-1/2 | 152b | 0 | 100 | 144c | 0 | 100 | 102 | 0 | 100 | 0 | 368d | 100 | 0 | 368d | 100 | 0 | 368 | 100 |
PA | 152 | 0 | 100 | 144 | 0 | 100 | NAe | NA | NA | 0 | 368 | 100 | NDf | ND | ND | NA | NA | NA |
Latex agglutination | 152 | 0 | 100 | 144 | 0 | 100 | NA | NA | NA | 0 | 368 | 100 | ND | ND | ND | NA | NA | NA |
Abbott HIV-1/2 3rd Gen. Plus.
One hundred two of 152 samples were paired with the 102 whole-blood samples.
One hundred two of 144 samples were paired with the 102 whole-blood samples.
All samples were paired with the whole-blood samples.
NA, not applicable.
ND, not done.