Figure 5.
Anti-PD-1+MTL-CEBPA treated mice display anti-tumor transcriptional profile in CT26 tumor (a) Segregation of tumor samples in the anti-PD-1+MTL-CEBPA group for nanostring analysis, selected regressing tumors are indicated with the green lines and progressing tumors are indicated with the red lines. Relative expression of (b) CEBPA, (c) Ifng, (d) Cd8a, (e) GzmB (f) Irf4, (g) Irf8, (h) Vegfa and (i) Ptgs2 mRNA compared to the control group. Statistical significance is indicated as * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001.