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Inhibition rate of Iripin-8 against selected serine proteases.
| Protease | k2 (M−1 s−1) | ±SE |
|---|---|---|
| Plasmin | 225,064 | 14,183 |
| Trypsin | 29,447 | 3508 |
| Kallikrein | 16,682 | 1119 |
| fXIa | 16,328 | 948 |
| Thrombin | 13,794 | 1040 |
| fXIIa | 3324 | 409 |
| fXa | 2088 | 115 |
| APC | 523 | 35 |
| fVIIa + TF | 456 | 35 |
| fIXa | N/A | N/A |
