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Polymorphisms influence gene expression. Polymorphism in the promoter region induces differences in promoter activity and therefore changes the expression level of Fc receptors. −386C−120A and −343G of FCGRIIB increase the expression level of FcγRIIb. −66T and −344T of FCERIA, −109T of FCERIB, and −237A of FCERIG increase the expression level of α, β, and γ subunit, respectively. −114C and +56C of FCAR increase the expression level of FcαRI.
