Figure 4.

MSEA and pathway analysis in COVID-19 patients. A summary plot for Quantitative Enrichment Analysis (QEA) is reported at the top of the figure showing the top 25 enriched terms for each disease condition: (a) mild, (b) moderate, and (c) severe. At the bottom, the pathway view shows for each condition all the matched pathways according to the p-values and the pathway impact values; the size of each pathway is a measure of the number of hits detected within that pathway. For both plots, p-values range from yellow (less significant) to red (more significant). (d) The Venn diagram shows the relationship between all the pathways identified in mild, moderate, and severe COVID-19 patients highlighting six terms common to all, and 11 terms common to moderate and severe.