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. 2021 Sep 3;13(17):4450. doi: 10.3390/cancers13174450

Figure 2.

Figure 2

The therapeutic outcomes of LFP and New FP. (A) Overall survival curve of the 150 patients treated with either LFP or New FP. The MST of 150 patients was 21.8 months. (B) Comparison of the survival curve between LFP and New FP group. The MST of LFP group was 16.1 months. The MST of New FP was 24.7 months. There was a significant difference between two groups (p < 0.05). (C) Comparison of Progression-free survival between LFP and New FP group. The PFS of LFP group was 5.4 months. The MST of New FP was 8.8 months. There was a significant difference between two groups (p < 0.05). (D) Comparison of the post-progression survival between LFP and New FP group. The PPS of LFP group was 6.8 months. The PPS of New FP was 11.5 months. There was no significant difference between two groups (p = 0.411). (E) The therapeutic response of LFP group. In LFP group, CR, PR, SD, and PD were 4, 43, 27, and 26%, respectively. (F)The therapeutic response of New FP group. In the New FP group, CR, PR, SD, and PD were 29, 47, 12, and 12%, respectively. (G) Comparison of the therapeutic response between LFP and New FP group. The ORR and DCR in LFP group were 47 and 74%, respectively. ORR and DCR in New FP group were 76% and 88%, respectively. There was a significant difference in ORR and DCR between two groups (p < 0.001 and p < 0.005, respectively.). LFP: Low dose CDDP plus 5-FU, MST: median survival time, CR: complete response, PR: partial response, SD: stable disease, PD: progressive disease, ORR: objective response rate, DCR: disease control rate. * p < 0.05, ** p < 0.01, *** p < 0.001, n.s.: not significant.