Table 4.
Univariate and multivariate analysis of the factors associate with the better therapeutic effects of either LFP or New FP (n = 150).
| Factors | CR or PR (n = 99) |
SD or PD (n = 51) |
Univariate Analysis p-Value |
Multivariate Analysis p-Value, (Logarithmic Value) |
|---|---|---|---|---|
| Age (<70 years) | 52/47 | 23/28 | 0.388 | - |
| Sex (Female) | 76/23 | 44/7 | 0.158 | - |
| HBs * Ag (−) | 16/83 | 13/38 | 0.159 | - |
| HCV ** Ab (+) | 58/41 | 22/29 | 0.092 | 0.54 |
| ALBI-grade (1) | 36/63 | 8/43 | 0.006 | 0.033, (2.17) |
| Platelet count (>11 × 104/μL) | 68/31 | 41/10 | 0.121 | 0.53 |
| AFP *** (<400 ng/mL) | 56/43 | 32/19 | 0.465 | - |
| DCP † (<1600 mAU/mL) | 46/53 | 39/12 | 0.0003 | 0.37 |
| Maximum tumor diameter (<70 mm) |
38/61 | 35/16 | 0.0004 | 0.26 |
| Tumor located segments (<3) | 45/54 | 17/34 | 0.0130 | 0.17 |
| Grade of PVTT †† (2nd or 1st branch) | 18/81 | 12/39 | 0.442 | 0.38 |
| Hepatic vein tumor thrombus (−) | 14/85 | 12/39 | 0.157 | - |
| Regimen (New FP †††) | 75/24 | 24/27 | 0.0005 | 0.0008, (3.12) |
* Hepatitis B virus, ** Hepatitis C virus, *** Alphaphetoprotein, † Des-gamma-Carboxy Prothrombin, †† Portal vein tumor thrombus, ††† DDP-H suspended with lipiodol plus 5-FU.