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. 2021 Sep 1;22(17):9511. doi: 10.3390/ijms22179511

Table 1.

Effect of resveratrol (R), piceatannol (ROH), and piceid (RG) at concentrations of 25 μM, IR (dose of 6 Gy), and their combinations on the transcription of genes involved in the apoptosis of MCF-7 cells. Gene expression was normalised to the HPRT housekeeping gene. The delta–delta Ct method was used to determine the relative levels of mRNA expression between the experimental samples and controls. The mean difference (*) was compared with the control and (#) with IR.

Control 6 Gy R R + 6 Gy ROH ROH + 6 Gy RG RG + 6 Gy
p53 1.00 ± 0.13 1.56 ± 0.11 * 1.78 ± 0.28 * 1.97 ± 0.20 *# 1.64 ± 0.27 * 1.74 ± 0.15 * 1.27 ± 0.12 * 1.50 ± 0.19 *
Caspase 3 1.00 ± 0.05 1.24 ± 0.12 * 1.19 ± 0.30 1.25 ± 0.16 1.04 ± 0.16 1.28 ± 0.03 * 0.87 ± 0.10 1.26 ± 0.16
Caspase 8 1.00 ± 0.04 1.50 ± 0.31 * 1.41 ± 0.42 * 2.07 ± 0.11 *# 1.13 ± 0.44 2.12 ± 0.12 *# 1.73 ± 0.41 * 1.94 ± 0.03 *#
Bax 1.00 ± 0.03 2.73 ± 0.26 * 2.36 ± 0.27 * 5.25 ± 0.46 *# 2.17 ± 0.46 * 4.05 ± 0.53 *# 1.48 ± 0.11 * 3.19 ± 0.42 *#
Bcl-2 1.00 ± 0.05 1.63 ± 0.26 * 1.53 ± 0.31 * 2.18 ± 0.39 *# 1.52 ± 0.31 * 2.02 ± 0.36 *# 1.25 ± 0.28 * 1.65 ± 0.26 *