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. 2021 Sep 4;13(17):4462. doi: 10.3390/cancers13174462

Figure 2.

Figure 2

Response to systemic and intratumoral CVA21 exposure in a murine model system. (A) RT-PCR time course of CVA21 systemically delivered IP and extracted from the blood of naïve mice. Purified CVA21 stock was used as a positive control for comparison (A,B,D). (B) RT-PCR time course comparison of CVA21 systemically delivered IP and extracted from the blood of naïve or immunized mice. (C) ELISA test for CVA21 antibodies in the serum of naïve and immunized mice. (D) RT-PCR time course of CVA21 in the blood following IT injection of naïve and immunized mice (3 mice/cohort).