Table 1.
E. coli | T. thermophilus | |||
---|---|---|---|---|
T, °C | kelbow, s−1 | kcca, s−1 | kelbow, s−1 | kcca, s−1 |
15 | 2.1 | 4.9 | 1.9 | 2.3 |
20 | 5.2 | 7.7 | 5.7 | 4.7 |
25 | 8.7 | 11.9 | 8.9 | 6.9 |
30 | 15.7 | 18.2 | 15.5 | 8.9 |
37 | 31.7 | 26.1 | 31.5 | 19.0 |
42 | 52.2 | 39.2 | 55.8 | 28.7 |
50 | 83.0 | 66.1 | 111.0 | 62.1 |
Rate constants determined at 5 µM EF-G; Standard error of the mean did not exceed ±5%; kelbow—rate constant of translocation detected by the label at the elbow region of tRNA; kcca—rate constant of translocation detected by the label at CCA-end of tRNA.