Figure 8.

Prediction of the docking position between two protein subunits of the galectin-2 dimer in two dimensions by using entropy-enthalpy compensation mechanism. (a) The galectin-2 dimer. (b) Distribution of hydrophobic (green areas) and hydrophilic (red and blue areas) surface areas on the two protein subunits at the docking site. (c,d) Projective images of distribution of hydrophobic and hydrophilic surface areas at the binding site. (e) The predicted maximized the overlapping of hydrophobic surface areas of the two projective images of the two protein subunits. (f) The prediction of the docking position between the two protein subunits in two dimensions, almost same as (b).