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. 2021 Sep 10;19:230. doi: 10.1186/s12916-021-02094-2

Table 3.

The monthly health service cost per patient of managing individuals with one, two and three conditions in an integrated one-stop clinic in Tanzania and Uganda. The mean costs and 95% confidence intervals reported are in 2020 US$

Cost component HIV only Diabetes Hypertension HIV + diabetes1# HIV + hypertension2# Diabetes + hypertension3# HIV + diabetes + hypertension4
Total monthly cost $34.21 (32.92, 35.59) $18.28 (17.52, 19.04) $18.60 (18.13, 19.08) $39.11 (33.99, 44.33) $32.18 (30.35, 34.07) $22.65 (21.86, 23.43) $36.38 (31.83, 41.07)
Personnel $7.36 (7.21, 7.52) $7.34 (7.08, 7.61) $8.15 (7.99, 8.32) $6.71 (6.15, 7.26) $6.62 (6.36, 6.90) $7.72 (7.49, 7.94) $6.37 (5.80, 6.95)
Medication $12.21 (11.60, 12.83) $2.11 (1.82, 2.41) $3.64 (3.43, 3.86) $18.54 (15.04, 22.36)a $14.12 (12.98, 15.30)b $4.99 (4.53, 5.46)c $16.98 (13.94, 20.45)d
Diagnostics $9.24 (8.30, 10.35) $3.64 (3.34, 3.97) $0.45 (0.32, 0.61) $9.65 (7.31, 11.99) $6.81 (6.08, 7.54) $3.87 (3.49, 4.23) $9.07 (7.08, 11.08)
Overheads $5.39 (5.16, 5.63) $5.19 (4.80, 5.59) $6.36 (6.04, 6.67) $4.21 (3.61, 4.86) $4.64 (4.33, 4.95) $6.07 (5.72, 6.42) $3.97 (3.39, 4.60)
 Administration $3.61 (3.39, 3.82) $3.69 (3.36, 4.03) $4.56 (4.27, 4.85) $2.43 (2.03, 2.95) $2.78 (2.52, 3.06) $4.19 (3.89, 4.49) $2.25 (1.87, 2.73)
 Equipment and furniture $0.38 (0.35, 0.41) $0.34 (0.29, 0.38) $0.40 (0.36, 0.43) $0.44 (0.31, 0.56) $0.39 (0.34, 0.44) $0.51 (0.46, 0.56) $0.38 (0.27, 0.50)
 Rental space $1.41 (1.37, 1.44) $1.16 (1.11, 1.22) $1.40 (1.36, 1.43) $1.34 (1.16, 1.51) $1.47 (1.40, 1.53) $1.37 (1.32, 1.42) $1.34 (1.16, 1.51)

aThe mean cost for antiretroviral therapy was $16.92 (95% CI 13.22, 20.84) and that of diabetes drugs was $1.62 (95% CI 0.96, 2.39)

bThe mean cost for antiretroviral therapy was $11.88 (95% CI 10.81, 12.99) and that of hypertension drugs was $2.24 (95% CI 1.91, 2.59)

cThe mean cost of diabetes medication was $1.75 (95% CI 1.44, 2.09) and that of hypertension medication was $3.24 (95% CI 2.95, 3.54)

dThe mean cost for antiretroviral therapy was $13.26 (95% CI 10.62, 16.15), hypertension drugs was $2.53 (95% CI 1.78, 3.35) and that of diabetes drugs was $1.19 (95% CI 0.64, 1.94)

1The cost of managing an individual with HIV and diabetes was − $13.39 (95% CI − 18.69, − 8.02) cheaper than managing two individuals with single conditions of HIV and diabetes, i.e., cost reductions of 25.5% (95% CI 15.4%, 35.5%)

2The cost of managing an individual with HIV and hypertension was − $20.63 (95% CI − 23.00, − 18.31) cheaper than managing two individuals with single conditions of HIV and hypertension, i.e., cost reductions of 39.1% (95% CI 35.1%, 42.9%)

3The cost of managing an individual with diabetes and hypertension was − $14.24 (95% CI − 15.42, − 13.05) cheaper than managing two individuals with single conditions of diabetes and hypertension, i.e., cost reduction of 38.6% (95% CI 36.0%, 41.1%)

4The cost of managing an individual with three conditions HIV, diabetes and hypertension is − $34.72 (95% CI − 39.53, − 29.75) cheaper than the cost of managing three individuals with single conditions of HIV, diabetes and hypertension, i.e., cost reductions of 48.8% (95% CI 42.1%, 55.3%). The overall cost of managing individuals with multi-morbidity (2 or 3 conditions) is − $20.74 (95% CI − 37.94, − 9.83) cheaper than the cost of two or more individuals with single conditions, i.e., cost reductions of 38.0% (95% CI 18.8%, 53.1%)

#The average additional cost per month of managing: (i) diabetes in an HIV-infected individual is $4.89 (95% CI − 0.36, 10.22), (ii) hypertension in HIV-infected individual is − $2.03 (95% CI − 4.33, 0.27) and (iii) hypertension in diabetic individuals is $4.37 (95% CI 3.27, 5.49)