Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 8;62(12):3. doi: 10.1167/iovs.62.12.3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright 2021 The Authors

This work is licensed under a Creative Commons Attribution 4.0 International License.

PMC Copyright notice

Figure 5. — N-cadherin immunolabeling showing disorganization of cellular architecture in Epha2-knockout mouse lenses. Representative confocal microscopy images of sections of lenses of 18-week-old Epha2^+/+ (A), Epha2^+/⁻ (B), and Epha2⁻^/⁻ (C), and 45-week-old Epha2^+/+ (D) and Epha2^+/⁻ (E) mice on C57BL/6J background immunolabeled with mouse anti-N-cadherin antibody (green) and DAPI (blue) to label the nuclei are shown. N-cadherin labeling delineated the cell boundary and showed well packed fiber cells arranged in meridional rows in 18, A, and 45-week-old Epha2^+/+, D, and 18-week-old Epha2^+/−, B, lenses. In contrast, it showed larger and disorganized fiber cells in 18-week-old Epha2^−/−, C, and 45-week-old Epha2^+/−, E, lenses. Sections probed with mouse IgG (negative control) revealed little or no non-specific labeling (F). Scale-bars 20 µm.