Table 3.
ROC analysis to determine cutoff values of laboratory data (mild to moderate I vs. ≥moderate II to severe).
| Cutoff Value | Sensitivity | Odds Ratio | AUC | |
|---|---|---|---|---|
| WBC | 5.5 × 109/L | 55.0% | 1.491 | 0.580 |
| Neutrophil | 3.5 × 109/L | 68.5% | 5.067 | 0.734 |
| Lymphocyte | 1.1 × 109/L | 65.8% | 3.990 | 0.695 |
| Hemoglobin | 14.0 g/dL | 57.0% | 1.898 | 0.580 |
| Platelet | 20.1 × 1010/L | 59.3% | 2.269 | 0.662 |
| PT-INR | 0.997 | 61.4% | 2.557 | 0.676 |
| APTT | 32.8 s | 53.2% | 1.316 | 0.530 |
| D-dimer | 0.60 μg/mL | 67.4% | 4.438 | 0.697 |
| CRP | 2.36 mg/mL | 85.0% | 33.65 | 0.946 |
| Procalcitonin | 0.069 ng/mL | 74.6% | 9.387 | 0.853 |
| Ferritin | 379 ng/mL | 78.3% | 14.12 | 0.872 |
| Total protein | 6.89 g/dL | 62.2% | 2.558 | 0.703 |
| Albumin | 3.73 g/dL | 81.7% | 20.44 | 0.882 |
| A/G ratio | 1.10 | 84.6% | 30.67 | 0.897 |
| T-Bil | 0.67 mg/dL | 66.5% | 4.248 | 0.711 |
| AST | 27.8 U/L | 76.2% | 11.86 | 0.794 |
| LDH | 222 U/L | 76.9% | 3.939 | 0.886 |
| Creatinine | 0.74 mg/dL | 62.3% | 3.163 | 0.630 |
| eGFR | 75.5 | 65.3% | 3.571 | 0.690 |
| Hemoglobin A1c | 6.11% | 73.9% | 10.63 | 0.788 |
WBC, white blood cell; PT-INR, prothrombin time—international normalized ratio; APTT, activated partial thromboplastin time; CRP, C reactive protein; A/G ratio, albumin/globulin ratio; T-Bil, total bilirubin; LDH, lactate dehydrogenase; eGFR, estimated glomerular filtration rate; Mild, without pneumonia; Moderate I, pneumonia without oxygen therapy; Moderate II, pneumonia with oxygen therapy; Severe, pneumonia with mechanical ventilation. AUC, area under the curve.