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. 2021 Aug 28;10(17):3864. doi: 10.3390/jcm10173864

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Serum biomarkers concentrations in IPF patients with stable and progressive disease over the second year of anti-fibrotic therapy. Notes: Panels showing serum biomarkers concentrations measured at 12-month and 24-month timepoints for: (A) KL-6, (B) SP-D, (C) MMP-7, (D) CA19-9, (E) CA-125, (F) CCL18, (G) periostin. * p < 0.05; ** p < 0.01. Abbreviations: KL-6—Krebs von den Lungen-6, SP-D—surfactant protein D, MMP-7—matrix metalloproteinase 7, CA19-9—cancer antigen 19-9, CA-125—cancer antigen 125, CCL18—chemokine (C-C motif) ligand 18, IPF—idiopathic pulmonary fibrosis.