Table 1.
Demographic characteristics, chronic comorbidities, clinical events and procedures along hospital admission, and univariate analysis of variables associated with HA-AKI stage 3 in the study group.
| Variables | Total | Stage 3 AKI | Non-Stage 3 AKI | Sig |
|---|---|---|---|---|
| n | 165,893 | 995 (0.6) | 164,898 (99.4) | |
| Gender: Men. (n) % | 74,962 (45.2) | 517 (52.0) | 74,445 (45.1) | <0.001 |
| Age (years). mean (SD) | 54.9 (20.6) | 67.1 (21) | 53.9 (19.9) | <0.001 |
| Chronic comorbidities | ||||
| Diabetes. (n) % | 30,357 (18.3) | 450 (45.2) | 29,907 (18.1) | <0.001 |
| Hypertension. (n) % | 65,554 (39.5) | 707 (71.1) | 64,847 (39.3) | <0.001 |
| Ischemic Heart Disease. (n) % | 12,428 (7.5) | 169 (17.1) | 12,259 (7.4) | <0.001 |
| Ischemic Cerebrovascular disease. (n) % | 11,446 (6.9) | 78 (7.8) | 11,368 (6.9) | 0.136 |
| Ischemic Peripheral vascular disease. (n) % | 8706 (5.2) | 93 (9.3) | 8613 (5.2) | <0.001 |
| Chronic digestive disease. (n) % | 9627 (5.8) | 51 (5.1) | 9576 (5.8) | 0.198 |
| Chronic liver disease. (n) % | 5667 (3.4) | 105 (10.6) | 5562 (3.4) | <0.001 |
| Chronic congestive heart failure. (n) % | 14,344 (8.6) | 256 (25.7) | 14,088 (8.5) | <0.001 |
| Chronic obstructive pulmonary disease. (n) % | 23,272 (14.0) | 424 (42.6) | 22,848 (13.9) | <0.001 |
| Malignancy. (n) % | 23,504 (14.2) | 304 (30.6) | 23,200 (14.1) | <0.001 |
| Rheumatologic disease. (n) % | 6828 (4.1) | 41 (4.1) | 6787 (4.1) | 0.529 |
| Urologic disease. (n) % | 11,926 (7.2) | 148 (14.9) | 11,778 (7.1) | <0.001 |
| Chronic Kidney disease stages | <0.001 | |||
| 0 + I | 137,385 (82.8) | 583 (58.6) | 136,802 (83) | |
| II | 16,252 (9.8) | 109 (11.0) | 16,143 (9.8) | |
| III | 9265 (5.6) | 175 (17.6) | 9090 (5.5) | |
| IV | 2991 (1.8) | 128 (12.9) | 2863 (1.7) | |
| Clinical variables along hospital admission | ||||
| Urgent admission. (n) % | 108,577 (65.5) | 947 (95.2) | 107,630 (65.3) | <0.001 |
| Anaemia. (n) % | 23,291 (14.0) | 379 (38.1) | 22,912 (13.9) | <0.001 |
| Acute respiratory failure. (n) % | 7803 (4.7) | 308 (31.0) | 7495 (4.5) | <0.001 |
| Acute Hearth failure (n) % | 6204 (3.7) | 241 (24.2) | 5963 (3.6) | <0.001 |
| SIRS. (n) % | 2358 (1.4) | 235 (23.6) | 2123 (1.3) | <0.001 |
| Circulatory shock. (n) % | 2018 (1.2) | 280 (28.1) | 1738 (1.1) | <0.001 |
| Major surgery. (n) % | 61,583 (37.1) | 408 (41.0) | 61,675 (37.4) | <0.001 |
| Exposure to contrast media. (n) % | 14,698 (8.9) | 280 (28.1) | 14,418 (8.7) | <0.001 |
| Exposure to nephrotoxic drugs. (n) % | 85,863 (51.8) | 677 (68.0) | 85,186 (51.7) | <0.001 |